Rhein CAS 478-43-3
Chrysophanol (CAS 478-43-3 ) is a natural anthraquinone compound extracted from plants such as rhubarb. Its chemical name is 1,8-dihydroxy-3-carboxyanthraquinone, with the molecular formula of C₁₅H₈O₆ and a molecular weight of 284.22. Basic physical and chemical properties • Appearance: Brown needle-like crystals, which turn into yellow needle-like crystals upon sublimation. Melting point: 321–322 °C. Boiling point: Approximately 597.8 °C (760 mmHg). • Density: Approximately 1.687 g/cm³. • Solubility: Almost insoluble in water; soluble in alkaline solutions, pyridine; slightly soluble in ethanol, benzene, chloroform, ether, petroleum ether. Main pharmacological activities and uses 1. Antitumor activity: It has inhibitory effects on melanoma in mice, Acanthamoeba cell culture, liver cancer, breast cancer, P388 leukemia cells, etc. 2. Antibacterial activity: It has inhibitory effects on Staphylococcus, Streptococcus, dysentery bacillus, etc. 3. ...